Application Of Enzyme Preparation in Oral Care
Feb 21, 2023
Oral care products are daily necessities for people to maintain oral health, and people continue to put forward higher demands for their quality. Since the vast majority of oral care products on the market contain a large number of synthetic ingredients, many synthetic raw materials can induce allergic reactions and even cause cancer risks in high doses or high concentrations. Biological enzymes are also gradually used in the field of oral care products because of their safety and high efficiency.
At present, the common biological enzymes used in oral-related products and care include glucose oxidase, glucanase, proteolytic enzyme, amylase, lysozyme and superoxide dismutase. Due to the specific action of enzymes, different biological enzymes can produce different effects. The application of biological enzymes in oral care products can not only whiten teeth, inhibit the growth of oral bacteria, and make gums healthy, but also be safer for the human body and more friendly to the environment, which meets the needs of consumers for the development of oral care products.
1. Application of glucose oxidase in toothpaste
Glucose oxidase can specifically catalyze glucose into gluconolactone and hydrogen peroxide in the presence of oxygen. Due to the residual glucose in the tooth stains, the above reactions can be located on the teeth stains in large quantities, and the pertinence is very strong, and the reaction site gradually releases hydrogen peroxide, so that too much hydrogen peroxide will not be produced all at once. Irritation to other tissues in the mouth. Glucose oxidase has good adhesion on teeth and can continue to work. The above reaction process can effectively remove glucose, so it can also play the role of preventing tooth decay and inhibiting dental plaque.
2. Application of glucanase in whitening toothpaste
Glucanase is a general term for a variety of enzymes that catalyze the hydrolysis of beta-glucan, which can effectively catalyze the hydrolysis of glucan into glucose. Bacteria in the human oral cavity, especially Streptococcus mutans, produce glucan, which attaches to the surface of teeth to form dental plaque. If plaque is not removed in time, long-term accumulation can easily lead to various oral problems such as black and yellow teeth, swollen gums and so on. Adding glucanase to toothpaste formulations can help break down plaque and remove tartar, thereby whitening teeth.
3. Application of protease in gingival toothpaste
Protease is a general term for a class of enzymes that hydrolyze protein peptide chains. The hydrolysis method is to hydrolyze the peptide bonds of protein molecules to free amino acids.
The protease is added to the toothpaste formula, and the protein in the food residue is hydrolyzed and broken by the protease, so that the food residue attached to the tooth surface becomes soft and can be removed by a brush with a toothbrush. Protease can also relieve gingival swelling and bleeding, so the application of protease to gum-protecting toothpaste has broad application prospects.
4. Application of lysozyme in fresh toothpaste
Lysozyme is an alkaline enzyme that can hydrolyze the polysaccharide of the cell wall of pathogenic bacteria. It mainly causes the disintegration of the cell wall by destroying the glycosidic bond in the peptidoglycan of the cell wall. Under the action of internal osmotic pressure, the cell ruptures, the contents escape, and the bacteria die. Lysozyme can also directly combine with negatively charged viral proteins to form complex salts with DNA, RNA and apoproteins to inactivate the virus. Therefore, lysozyme has antibacterial, anti-inflammatory, antiviral and other effects. There are abundant microorganisms in the human oral cavity, and microorganisms are the source of various problems in the oral cavity. Lysozyme has the effect of inhibiting oral bacteria. It can adsorb to the cell wall of bacteria, and rupture the cell wall through hydrolysis, leading to bacterial cell death, thereby killing bacteria. Therefore, adding lysozyme to the toothpaste formula can utilize its bactericidal effect to reduce the growth of oral bacteria and refresh the breath.
